The latest example of the impact of BMTPlus enabled knowledge management is the acceptance of our research in the official journal of the American Society of Blood and Marrow Transplantation, the Transplantation and Cellular Therapy Journal, a publication with an impact factor of 6+. World health organisation has declared that antimicrobial resistance is one of the top 10 global public health threats facing humanity. On this very pertinent topic, our paper titled "Do weekly surveillance cultures contribute to antibiotic stewardship and correlate with outcome of bone marrow transplantation in children – a multicentre real-world experience of 5 years from the Indian subcontinent?" presents real-life evidence on how a measure thought to help fight antimicrobial resistance has not worked. In fact, it may be doing more harm than good.
This is the 3rd finding facilitated by BMTPlus accepted and published in Transplantation and Cellular Therapy Journal alone, the first two being our finding on the need to switch to high-resolution HLA typing even for related donors and the second one being the identification of splenomegaly as a risk factor for rejection in transplantation for thalassemia.
BMTPlus has enabled harmonizing the care delivery for complex medical procedures of bone marrow transplantation since 2013. The platform is a rare example of a software application that has standardization of clinical pathways and enabled evidence-based medicine across a diverse range of users and locations. The platform has not only played a pivotal role within the quality strategy (in-line The Foundation for the Accreditation of Cellular Therapy (FACT) and The Joint Accreditation Committee ISCT-Europe & EBMT (JACIE) standards) of institutions but has also enabled collaboration. Users are able to connect better, combine their efforts, outcomes, and share learning. A key success has been the ability of the platform to unlock the potential of data for improving health outcomes.
A study like the one that has been summarized would take years of planning and extensive effort to complete if it were to be done using the traditional approach. Using BMTPlus, the participants collaborated, shared protocols, received compliance alerts, and experienced periodic seamless reviews of the outcomes. A practice that was thought to be very effective elsewhere was successfully adopted and evaluated effectively in the local context. This again is a powerful example of the use of real-world data (RWD) and real-world evidence (RWE).
This report is the latest among a series of findings that have been peer-reviewed and published, even as users continue to use system facilitated analysis on a day-to-day basis to improve patient outcomes. The platform has proven to play an important role in enhancing patient safety.
One of the users remarked - "This is the first time that I feel that all the hard work and all the data that we put together on a day-to-day basis does not actually go down a sinkhole. We are beginning to see how the individual records come together to improve the care that we give to the next patient. We seem to be connecting the data dots."
It's reassuring to see progress being made in achieving effective knowledge management.